Pneumococcal Conjugate Vaccines and Otitis Media
نویسندگان
چکیده
1Global Vaccine Development, GlaxoSmithKline Vaccines, 1300 Wavre, Belgium 2Department of Pathophysiology and Transplantation, University of Milan and Fondazione IRCCS Cà, Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy 3Paediatric Infectious Diseases, Infection Control and Epidemiology Unit, Université Libre de Bruxelles, 1020 Brussels, Belgium 4Multi-Centre Otitis Media Study Group, Department of Psychology, University of Cambridge, Cambridge CB2 3EB, UK
منابع مشابه
New vaccines for the prevention of pneumococcal infections.
Streptococcus pneumoniae is a major cause of acute otitis media, pneumonia, bacteremia, and meningitis. Because in recent years antibiotic-resistant pneumococcal strains have been emerging throughout the world, vaccination against pneumococcal infections has become more urgent. The capsular polysaccharide vaccine that has been available is neither immunogenic nor protective in young children an...
متن کامل[Conjugate pneumococcal vaccines and influence on the ear, nose and throat area].
The importance of anti-pneumococcal vaccines has increased due to the gradually increasing incidence rate of pneumococcal infections and their antibiotic resistance. Conjugate pneumococcal vaccine began to be used routinely in the USA in 2000. An important property of this conjugate vaccine is the ability to create immunity in infants after two months. Thus, conjugate vaccines allow us to prote...
متن کاملNew vaccines against otitis media: projected benefits and cost-effectiveness.
OBJECTIVE New vaccines that offer protection against otitis media caused by nontypeable Haemophilus influenzae and by Moraxella catarrhalis are under development. However, the potential health benefits and economic effects of such candidate vaccines have not been systematically assessed. METHODS We created a computerized model to compare the projected benefits and costs of (1) the currently a...
متن کاملAcute otitis media caused by antibiotic-resistant Streptococcus pneumoniae in southern Israel: implication for immunizing with conjugate vaccines.
The potential coverage of antibiotic-resistant pneumococci causing acute otitis media (AOM) by 7-, 9-, and 11-valent conjugate pneumococcal vaccines was studied in southern Israel. A total of 876 cases of pneumococcal AOM were studied in the context of various clinical conditions. Of the isolates, 68% were resistant to >/=1 drug, 61% were resistant to penicillin, and 13% were resistant to >/=3 ...
متن کاملErratum to “Pneumococcal Conjugate Vaccines and Otitis Media: An Appraisal of the Clinical Trials”
Streptococcus pneumoniae is the predominant otitis media pathogen and its prevention through effective vaccination could diminish childhood illness and antibiotic use. This paper reviews 5 pneumococcal conjugate vaccine (PCV) trials that used otitis media as an endpoint: Northern California Kaiser Permanente (NCKP; vaccine, 7-valent PCV [PCV7]-CRM); Finnish Otitis Media (FinOM; vaccines, PCV7-C...
متن کاملAntibiotic resistance and the potential impact of pneumococcal conjugate vaccines.
Streptococcus pneumoniae is a major cause of morbidity and mortality in young children throughout the world, causing both invasive (meningitis, bacteraemia) and non-invasive (pneumonia, acute otitis media, sinusitis) infections. Over the past few decades, the global emergence of antibiotic-resistant pneumococcal strains has complicated disease management. Thus, healthcare practitioners have beg...
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عنوان ژورنال:
دوره 2012 شماره
صفحات -
تاریخ انتشار 2012